Corning Costar 3690 96-Well Half-Area High Binding Microplate (EIA/RIA) The Corning Costar 3690 is a precision-engineered 96-well microplate designed for high-sensitivity Immunoassays (EIA/RIA) where reagent conservation is a priority. Featuring a unique "Half-Area" well geometry, this plate allows researchers to reduce sample and reagent volumes by 50% while maintaining the standard path length of a 96-well format. The specialized High Binding surface is modified to enhance the adsorption of medium-to-large biomolecules (including IgG), ensuring superior coating efficiency and high signal-to-noise ratios. Manufactured from crystal-grade polystyrene, the 3690 is the ideal choice for high-throughput screening, antibody titrations, and diagnostic assay development. Technical Performance and Design Half-Area Reagent Savings: The reduced well diameter allows for optimal performance with working volumes as low as 25 µl, significantly reducing the cost per well for expensive antibodies and rare samples. High Binding Surface Chemistry: The polystyrene surface is vacuum-gas plasma treated to increase its binding capacity for proteins and molecules with ionic groups or hydrophobic regions (400–500ng IgG/cm²). Exceptional Optical Clarity: The clear, flat-bottom design ensures a distortion-free optical path, making it fully compatible with standard top-reading and bottom-reading microplate readers. Standardized Footprint: Despite the half-area well design, the plate conforms to standard ANSI/SLAS dimensions, ensuring seamless integration with automated liquid handlers and robotic stackers. Product Specifications Catalog Number: 3690 Format: 96-Well Half-Area Clear Flat Bottom Surface Treatment: High Binding (Non-TC Treated) Total Well Volume: 190 µl Recommended Working Volume: 25 to 125 µl Growth/Binding Area: 0.158 cm² per well Sterility: Non-sterile (Standard for EIA/RIA assays) Packaging: 25 Plates per Bag / 100 Plates per Case Key Benefits & Applications Cost-Efficient ELISA: Specifically designed for assays using high-value reagents where reducing volume from 100 µl to 50 µl provides significant long-term savings. Maximized Signal Intensity: The narrow well diameter increases the concentration of the analyte over the binding surface, often leading to improved sensitivity in colorimetric assays. Diagnostic Assay Development: Used extensively in the development of commercial assay kits requiring high reproducibility and well-to-well consistency. Ease of Automation: The rigid sidewall construction and standard footprint prevent warping and ensure reliable performance during vigorous automated washing and shaking cycles. All product names, logos, and brands are property of their respective owners.
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