Anti-DM1 Mouse mAb _ 31901ES

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DM1, also known as maytansine, is a microtubulin inhibitor, potentially conjugated with monoclonal antibodies to form antibody-drug conjugates(ADCs). DM1 as the toxin component of ADCs, exhibits strong anti-tumor activity by inhibiting cell division and inducing apoptosis. Specifications Cat.No. 31901ES60/31901ES80 Size 100 μg/1 mg Source Monoclonal anti-DM1 antibody, is produced from a hybridoma which was obtained from a mouse immunized with DM-1. Buffer 1×PBS, pH7.4. Type Monoclonal Antibody Isotype IgG1 Host Mouse Concentration 1 mg/mL Purity ＞94% as determined by reduced SDS-PAGE ＞97% as determined by non-reduced SDS-PAGE > 98% as determined by SEC-HPLC Activity EC50=8.6 ng/mL by ELISA Application ELISA Storage This product should be stored at -25~-15℃ for one year, do not freeze. Notes This product is for research use only. Please operate with lab coats and disposable gloves, for your safety. Data SDS-PAGE Anti-DM1 mouse mAb on SDS-PAGE under reduced condition. The purity is 93.4%； Anti-DM1 mouse mAb on SDS-PAGE under non-reduced condition. The purity is 98.0%. SEC-HPLC The purity of Anti-DM1 mouse mAb is 96.8% as determined by SEC-HPLC. ELISA Data Dose response curve shows that the EC50 of Anti-DM1 mouse mAb is 8.6 ng/mL. Show more