Anti-DXD Mouse mAb _ 31902ES

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Exatecan（DXD）is a synthetic derivative of the naturally occurring compound camptothecin. it binds to the topoisomerase 1-DNA complex, preventing DNA re-ligation which results in th e accumulation of DNA strand breaks and ultimately leads to cell death. Specifications Cat.No. 31902ES60/31902ES80 Size 100 μg/1 mg Source Monoclonal anti-DXD antibody, is produced from a hybridoma which was obtained from a mouse immunized with DXD. Buffer 1×PBS, pH7.4. Type Monoclonal Antibody Isotype IgG1 Host Mouse Concentration 1 mg/mL Purity ＞98% as determined by reduced SDS-PAGE ＞98% as determined by non-reduced SDS-PAGE > 98% as determined by SEC-HPLC Activity EC50=41.4 ng/mL by ELISA Application ELISA Storage This product should be stored at -25~-15℃ for one year, do not freeze. Notes This product is for research use only. Please operate with lab coats and disposable gloves, for your safety. Data SDS-PAGE Anti-DXD mouse mAb on SDS-PAGE under reduced condition. The purity is 98.2%； Anti-DXD mouse mAb on SDS-PAGE under non-reduced condition. The purity is 98.4%. SEC-HPLC The purity of Anti-DXD mouse mAb is 99% as determined by SEC-HPLC. ELISA Data Dose response curve shows that the EC50 of Anti-DXD mouse mAb is 41.4 ng/mL. Show more