5-MTHF ES provides 17,000 mcg of 5-MTHF (5-methyltetrahydrofolate) per serving. 5-MTHF is the most biologically active form of the water-soluble B vitamin, folate; and it may be the preferred form for those with variations in digestion, absorption, or folate metabolism. Data suggest that in comparison to synthetic folic acid, 5-MTHF increases plasma folate more effectively. In this formula, 5-MTHF is provided as Quatrefolic®—the glucosamine salt of 5-MTHF. Quatrefolic has demonstrated greater stability, solubility, and bioavailability when compared to calcium salt forms of 5-MTHF.* Supports Healthy Serum Folate* Supports the Conversion of Homocysteine to Methionine* Supports Methylation* Supports Nervous System and Oral Health* Supports Normal Cellular Proliferation (including red blood cells)* Supports a Healthy Pregnancy Outcome* Suggested Use:Take one to two capsules daily, or as directed by your healthcare professional. Serving Size: 2 CapsulesAmount Per ServingFolate … 17,000 mcg DFE(as (6S)-5-methyltetrahydrofolic acid, glucosamine salt)Other Ingredients: Microcrystalline cellulose, capsule (hypromellose and water), stearic acid, magnesium stearate, and silica. Formulated to Exclude: Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.