Y-27632 (Y27632, Y 27632) is a potent, selective, ATP-competitive ROCK inhibitor, acts on ROCK1 (p160ROCK) (Ki=140 nM) and ROCK-II (IC50=800 nM), and inhibits PRK2 activity. The effect of Y-27632 on human embryonic stem cells (hES) significantly reduces cell separation-induced apoptosis and improves the efficiency of clone formation. Y-27632 can also promote the proliferation of human corneal epithelial cells cultured in vitro. Features Purity≥98% Standardized production, using factory mass production mode Specifications Cat.No. 53006ES03/53006ES08/53006ES10/53006ES50/53006ES60 Size 1 mg/5 mg/10 mg/50 mg/100 mg Synonym Y27632; Y 27632 Target ROCK-I; ROCK-II CAS No. 146986-50-7 Molecular formula C14H21N3O Molecular weight 247.34 Appearance solid powder Purity ≥98% Solubility soluble in DMSO Structure Components Components No. Name 53006ES03 53006ES08 53006ES10 53006ES50 53006ES60 53006 Y-27632 1 mg 5 mg 10 mg 50 mg 100 mg Shipping and Storage The Y-27632 products should be stored at -15～-25℃ for 2 years. Avoid repeated freeze-thaw cycles. Documents: Safety Data Sheet 53006_MSDS_HB20250210 _EN.pdf Manuals 53006_Manual_HB20250210 _EN.pdf
