Douglas Laboratories 7-Keto Supports Healthy Weight Management and Body Composition 7-Keto® DHEA Metabolite, provided by Douglas Laboratories, supplies 100 mg of 3-acetyl-7-oxodehydroepiandrosterone (a naturally occurring metabolite of DHEA) in each capsule to support healthy weight management. Ingredients Serving Size: 1 Vegetarian Capsule Amount/Serving 7-Keto (3-Acetyl-7-oxo-dehydroepiandrosterone) 100 mg Other Ingredients: Cellulose and vegetable stearate. Does Not Contain: Yeast, gluten, soy, milk/dairy, corn, sodium, sugar, starch, artificial preservatives, artificial flavoring, or genetically modified organisms (GMOs). Suggested Use As a dietary supplement, adults take 1 capsule twice daily or as directed by your healthcare professional. Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use. Storage: Store in a cool, dry place, away from direct light. Keep out of reach of children. More Info. The 7-Keto® metabolite of DHEA is a natural, non-steroidal molecule that is produced in the body from DHEA. This metabolite is chemically different from DHEA and cannot convert back into DHEA in the body. Studies indicate that 7-Keto may be useful in supporting healthy weight management while following an exercise program and healthful diet. During the normal aging process, natural levels of 7-Keto begin to decline. Research in animals also shows that aging may have an effect on the body’s ability to maintain optimum thermogenesis (fat burning) activity. Recent research indicates that 7-Keto may play important roles in supporting a healthy weight by activating thermogenic enzymes. Several clinical studies have been conducted in healthy overweight adults. In one double-blind, placebo-controlled study, subjects given 200 mg of 7-Keto reduced body weight more significantly compared with placebo while maintaining a diet and exercise regimen. No significant changes in blood glucose, hormonal levels, liver enzymes, or renal function were experienced, and no adverse side effects were reported. In another double-blind, placebo-controlled study, after 8 weeks, subjects on an exercise program and healthful diet lost significantly more weight compared with placebo. The natural metabolite 7-Keto was again well tolerated, and no significant adverse effects were reported. Additional studies indicate that 7-Keto cannot convert into other steroid hormones in the body and does not affect estrogen, testosterone, or progesterone levels in the body.