PC Version Array: Clear polycarbonate substrate, standard thickness 0.51mm or high numerical aperture (HNA) series of 0.13mm Each of the 8 wells has two sets of 20 circular 250 μm diameter active electrodes located on inter-digitated fingers to provide measurements of cells upon a total of 40 electrodes. Each well has a substrate area of 0.8 cm2 and a maximum volume of 600 μL. On average, with a confluent layer, approximately 2000 to 4000 cells will be measured by the electrodes. The 10E+ arrays are designed to monitor larger numbers of cells, sampling over the entire bottom of the well. Because of the relatively high number of cells, impedance fluctuations due to micromotion are smoothed out and do not obscure subtle changes in impedance due to the experimental conditions. Applications include: • Cell Attachment and Spreading • Cell proliferation • Cell Differentiation • Cell-ECM Protein Interactions • Barrier function • Signal transduction assays • Cell Invasion • Cytotoxicity
