Recombinant Mouse IL-13 Protein _ 90151ES

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Interleukin-13 (IL-13) is an immunomodulatory cytokine primarily produced by activated Th2 cells, as well as mast cells and NK cells. IL-13 exerts anti-inflammatory effects on mono cytes and macrophages by inhibiting the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6, and IL-8. Additionally, IL-13 enhances B cell proliferation and induces isotype switching, thereby increasing IgE production. This recombinant mouse IL-13 is supplied as a lyophilized powder. It features high activity, high purity, low endotoxin levels, and is tag-free. Components Components No. Name 90151ES05 90151ES10 90151ES50 90151ES60 90151ES76 90151 Recombinant Mouse IL-13 Protein 2 μg 10 μg 50 μg 100 μg 500 μg Specifications Synonyms BHR1interleukin-13, IL13, interleukin 13, MGC116786, NC30, P600 Source E.coli-derived Mouse IL-13, Pro22-Phe131, with an N-terminal Met. Accession P20109 Molecular Weight Approximately 12.3 kDa. AA Sequence MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F Endotoxin < 1.0 EU/μg by the LAL method. Purity > 97% as determined by SDS-PAGE and HPLC analyses. Biological Activity The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 4 ng/mL, corresponding to a specific activity of > 2.5 × 105 IU/mg. Fully biologically active when compared to standard. Formulation Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. Tag No Tag Physical Appearance White lyophilized powder Storage This product should be stored at -25~-15℃ for 1 year. Once reconstituted under sterile conditions, it can be stored at 2 ~ 8°C for 7 days, or at -85 to -65°C for 3 months. Reconstitution Instructions Centrifuge the vial briefly before opening to pellet the contents at the bottom. Reconstitute with sterile deionized water or PBS to a final concentration of 0.1–1.0 mg/mL. Further dilution can be performed as needed for downstream applications. For long-term storage, it is recommended to add a carrier protein (e.g., 0.1% BSA) to the dilution buffer. After initial reconstitution, aliquot the solution into single-use portions and store at -80°C to avoid repeated freeze-thaw cycles. Notes 1. This product is for research use only. 2. Please operate with lab coats and disposable gloves，for your safety. Documents: Safety Data Sheet 90151_MSDS_HB260622 Manuals: 90151_Manual_HB20260622 Show more