Recombinant Human BAFF Protein, His tag _ 90604ES

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Description The human BAFF protein, or B-cell activating factor, is a crucial cytokine that plays a significant role in regulating the immune system and promoting B-cell survival a nd maturation. BAFF is primarily produced by immune cells, including monocytes, macrophages, and dendritic cells. It binds to specific receptors on B cells, allowing their development and preventing apoptosis (cell death). BAFF also influences the production of antibodies and helps regulate the balance of different B-cell subsets. Product information Synonyms BLyS, CD257, TNFSF13B, TNFSF20, TALL-1, BLys, THANK, BAFFB-cell activating factor, ZTNF4 Uniprot No. Q9Y275 Source HEK293 cells-derived human BAFF protein, Ala134-Leu285, with N-terminal His tag. Molecular Weight Approximately 18.12 kDa. Purity > 90% as determined by SDS-PAGE. Biological Activity Human BCMA, His tag immobilized on CM5 chip can bind BAFF, His tag, with an affinity constant of 1.55 x 10-9 M as determined in a SPR assay (Biacore 8K). Endotoxin < 0.1 EU per 1μg of the protein by the LAL method. Formulation Lyophilized from a 0.2 μm filtered concentrated solution in PBS. Reconstitution Centrifuge tubes before opening. Dissolve lyophilized protein with PBS. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles. Storage The product should be stored at -25~-15℃ for 1 year from date of receipt. 2-7 days, 2 ~8 °C under sterile conditions after reconstitution. 3 months, -25~-15℃ under sterile conditions after reconstitution. Notes 1.Please operate with lab coats and disposable gloves, for your safety. 2.This product is for research use only. Show more