Recombinant Mouse Monocyte Chemotactic Protein-2/CCL8 (Mouse MCP-2/CCL8) _ 90982ES

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The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate m onocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Murine MCP-2 is an 8.5 kDa protein containing 74 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Product Properties Synonyms Small-inducible Cytokine A8 Accession Q9Z121 GeneID 20307 Source E.coli-derived Mouse MCP-2 protein,Gly24-Pro97. Molecular Weight Approximately 8.5 kDa. AA Sequence GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV FQTKQGMSLC VDPTQKWVSE YMEILDQKSQ ILQP Tag None Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder. Purity > 97% by SDS-PAGE and HPLC analyses. Biological Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-100 ng/mL. Endotoxin Show more