The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of malignant tumors that highly express LMP2. Specifications Synonyms MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9 Uniprot No. A0A140T913(HLA-A*02:01)&P61769(B2M)&CLGGLLTMV] Source Recombinant Human LMP2 (HLA-A*02:01) Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and CLGGLLTMV peptide Source The protein has a predicted MW of 50.3 kDa. Due to glycosylation, the protein migrates to 52-56 kDa based on Tris-Bis PAGE result. Purity > 95% as determined by SDS-PAGE and HPLC. Endotoxin
