Human Siglec-2/CD22 Protein, hFc Tag

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CD22, a molecule belonging to the SIGLEC family of lectins, is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surfac e of mature B cells. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. Specifications Synonyms CD22 molecule; CD22; Siglec-2; B-cell receptor CD22; BL-CAM; SIGLEC2; SIGLEC2FLJ22814 Uniprot No. P20273-1 Source Recombinant Human Siglec-2/CD22 Protein is expressed from HEK293 cells with hFc tag at the C-terminal. It contains Asp20-Arg687. Molecular Weight The protein has a predicted MW of 101.9 kDa. Due to glycosylation, the protein migrates to 120-130 kDa based on SDS-PAGE result. Purity > 95% as determined by SDS-PAGE and HPLC. Endotoxin Show more