Human VEGFR2/KDR Protein, His tag

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VEGFR2 is a receptor for vascular endothelial growth factor (VEGF) that mediates virtually all known cellular responses to VEGF. VEGFR2 is mainly expressed in endothelial cells and is up-regulated in tumor vascular system. Inhibition of VEGFR2 activity and its downstream signal is an important target for the treatment of angiogenic diseases. Specifications Synonyms KDR;Flk-1 Uniprot No. P35968 Source Recombinant Human VEGFR2 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Ala 20-Glu 764. Molecular Weight The protein has a predicted MW of 85.22 kDa. And it migrates as 130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Purity > 95% as determined by SDS-PAGE. Endotoxin Show more