Human IL12RB1 is an autosomal gene that is essential for mycobacterial disease resistance and T cell differentiation. IL12RB1 pre-mRNA is processed into either IL12RB1 Isoform 1 (IL12Rβ1, a positive regulator of IL12 responsiveness) or IL12RB1 Isoform 2 (a protein of heretofore unknown function). Specifications Synonyms IL-12R-beta-1; IL-12RB1; IL12R; IL12RB; CD212; IL-12R subunit beta-1; IL-12R-BETA1; MGC34454;IL-12R-β-1; IL-12R subunit β-1; IL-12R-β1 Uniprot No. P42701-1 Source Recombinant Human IL-12 R beta 1/CD212 Protein is expressed from HEK293 cells with His tag at the C-terminal. It contains Cys24-Glu540. Molecular Weight The protein has a predicted MW of 58.2 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on SDS-PAGE result. Purity > 95% as determined by SDS-PAGE and HPLC. Endotoxin