Product Properties Alternative Names ACVRLK1, ORW2, ALK1, ALK-1, EC 2.7.11, HHT, HHT2, SKR3, TSR-I, ACVRL1 Species Cynomolgus Expression Sequence Asp22-Gln118 Accession XP_005570958.1 Tag C-His Expression System HEK293 Molecular Weight The protein has a predicted MW of 11.86 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on SDS-PAGE result. Purity > 95% as determined by SDS-PAGE and HPLC. Endotoxin < 1.0 EU per μg by the LAL method. Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. Appearance Lyophilized Powder Biological Activity 【ELISA Data】Immobilized Human GDF-2, No Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Cynomolgus ALK-1, His Tag with the EC50 of 13.6ng/ml determined by ELISA . Reconstitution Method Before opening, centrifuge briefly. Reconstitute the lyophilized protein with distilled water to a concentration exceeding 100 μg/mL. Aliquot after initial reconstitution to avoid repeated freeze-thaw cycles. Features High purity, high activity, low endotoxin, high batch-to-batch consistency Storage Store at -25 ~ -15℃, valid for 1 year after receipt. After reconstitution, store at -85 ~ -65℃ under sterile conditions, valid for 3 months.
