Dendritic Cell Lectin (DLEC), also known as BDCA-2, CD303, HECL, and alternatively designated as CLEC4C/CLECSF11/CLECSF7, is a 38 kDa type II transmembrane protein belonging to the C-type lectin family. The expression of DLEC is primarily restricted to plasmacytoid dendritic cells (pDCs) and is downregulated as these cells mature. pDCs are integral to the innate immune response, particularly in the production of IFN-alpha/beta upon exposure to Toll-like receptor (TLR) 7 and TLR9 agonists, such as microbial CpG DNA Specifications Cat.No. 96514ES25 / 96514ES60 / 96514ES76 Size 25 μg / 100 μg / 500 μg Components Name 96514ES25 96514ES60 96514ES76 Recombinant Human BDCA2/DLEC4C Protein,hFc Tag 25 μg 100 μg 500 μg Performance parameters Synonyms BDCA2,BDCA-2,CD303,CLEC4C,CLECSF11 Species Human Expression Sequence: Asn45-Ile213 with Human IgG1 Fc Tag at N-Terminus Accession Q8WTT0 Tag N-hFc Tag Expression System HEK293 Molecular Weight 50-60 kDa (Reducing) Purity > 95% as determined by SDS-PAGE. Endotoxin
