Biodesign is reshaping a millennia-old relationship between architecture and nature, shifting the field toward adaptive, collaborative modes of practice grounded in reciprocity and ecological responsibility. This issue of Architectural Design traces that shift from speculative metaphor to an operational design framework, arguing that architecture is undergoing a fundamental reorientation around living systems.Here, biology becomes collaborator, model and medium, rather than a passive resource to be extracted. Contributors propose an architecture that behaves metabolically—growing, digesting, adapting and decaying in concert with ecological cycles—positioning architects as cultivators of biological processes and regenerative material flows. Across living biocomposites, biodigital platforms and relational, biotic architectures, the issue advances an ethics, politics and aesthetics that decenter the human and conceive the built environment as continuous with, and accountable to, the ecologies it sustains.ISBN 9798994298206. Axiomatic Editions. pb. .not yet published
