Promotes cellular homeostasis Scientifically proven to help reduce chronic pain and inflammation Natural long-chain fatty acid amide generally produced in response to various triggers, including inflammation Offers a multi-pronged approach to activating and maintaining the endocannabinoid system Has been the subject of over 300 medical studies over 80 years Available in capsules for your convenience Palmitoylethanolamide (PEA) is a long-chain fatty acid naturally produced by the body, but also found in foods like egg yolk, soybean, and sunflower oils. This molecule, studied for eighty years for its unique and varied health benefits, is now receiving particular attention due to its crucial role in the endocannabinoid system (ECS). The ECS is a lipid communication network with critical physiological functions. It is a signaling network that communicates with other bodily systems, helping to regulate them. PEA is an endocannabinoid produced locally by cells and accumulates in tissues following any injury, physical stress, or pain. By inhibiting the activation of mast cells that cause further inflammation (such as histamine release), PEA acts as a powerful anti-inflammatory agent. This unique molecule has other direct and indirect mechanisms of action; it even enhances the action of other endocannabinoids through its "entourage effect." The PEA molecule has been clinically demonstrated for pain relief in knee osteoarthritis as well as for reducing lower back pain symptoms. This potent little molecule is well-tolerated by athletes, children, and the elderly. AOR leads the way by transforming the impressive and evolving research on the positive effects of PEA on the human endocannabinoid system to provide its valued clientele with a safe therapeutic formula to combat chronic pain and systemic inflammation. AOR's Active PEA is produced in Italy and sourced from ecologically sustainable Malaysian palm oil, purified and responsibly processed for optimal bioavailability.