NeuroScience AdreCor with Licorice Root Increases cortisol levels and provides non-glandular ingredients important for adrenal health, energy, wakefulness, and stress management. The Science: In response to stress, the sympathetic nervous system (SNS) and hypothalamic-pituitary-adrenal (HPA) axis signal to the adrenals to release catecholamines and cortisol Prolonged stress is associated with dysregulation of the HPA axis, which can affect catecholamine and cortisol levels Ingredients Serving Size: 3 Capsules Amount/Serving Vitamin C (as ascorbic acid) 300 mg Niacin (as niacinamide) 6 mg NE Vitamin B6 (as pyridoxal 5'-phosphate) 12 mg Folate (as L-5-methyltetrahydrofolate, calcium salt) 220 mcg DFE Vitamin B12 (as methylcobalamin) 60 mcg Pantothenic acid (as D-calcium pantothenate) 300 mg Magnesium (as magnesium glycinate) 14 mg Zinc (as zinc bisglycinate chelate) 3 mg Glycyrrhizic acid (from Licorice root extract) 120 mg Proprietary Blend: 587 mg L-histidine, L-methionine, L-tyrosine, Rhodiola rosea extract (root) (5% rosavins), and Green tea extract (Camellia sinensis) (leaf) (65% epigallocatechin gallate) Other Ingredients: Vegetable capsule (hypromellose, water), micro-crystalline cellulose, and magnesium stearate (vegetable source). Suggested Use Take 1-3 capsules one to two times daily or as directed by your healthcare provider. Do not exceed the suggested use Warning: If you have cardiovascular concerns or if you are pregnant or nursing, consult your healthcare provider before use. Keep out of reach of children. Storage: This product has a tamper-evident seal under the cap. Do not use if the seal is broken or missing. Store at room temperature, in a dry place. More Info. AdreCor with Licorice Root and adrenal health Contains amino acids and vitamins important for the synthesis of adrenal hormones and neurotransmitters 5-MTHF (from Quatrefolic®) and vitamin B12 are important for methylation processes including the synthesis of catecholamines Niacin, vitamin C, and 5-MTHF help protect and regenerate tetrahydrobiopterin (BH4) from oxidation Pantothenic acid is the precursor to coenzyme A (CoA), a coenzyme important for energy production and hormone synthesis Catecholamines play an important role in mood, energy, memory, attention and cognition Cortisol, HPA axis, and fatigue Cortisol awakening response (CAR) refers to the sharp increase in cortisol levels observed immediately following awakening CAR function is thought to be important in regaining arousal after sleep and preparing the body for forthcoming bioenergetic demands Cortisol curves lacking a robust CAR are indicative of HPA axis dysregulation and have been correlated with feelings of fatigue AdreCor with Licorice Root increases cortisol levels Participants (n = 19) were prescreened for low cortisol levels AdreCor with Licorice Root (3 capsules, twice daily) was taken for four consecutive days Mean total cortisol levels (area under the curve - AUC) were significantly higher on Day 5 compared to Day 0 (p = 0.004)
