SkinCeuticals A.G.E. Interrupter Advanced is a concentrated anti-wrinkle cream designed to improve the look of fine lines, deep wrinkles, visible creases, loss of firmness, uneven tone, dullness, and aging-looking skin affected by glycation. Powered by 18% Proxylane, 4.25% wild fruit flavonoids, glycyrrhetinic acid, 3% HEPES, 1% niacinamide, and shea butter, it supports smoother, firmer, more radiant-looking skin. Clinically proven to help reverse collagen glycation by up to 33%, this rich anti-aging cream delivers 24-hour hydration with a satin finish while targeting visible wrinkles across key facial zones, including forehead wrinkles, crow’s feet, nasolabial folds, marionette lines, and glabellar lines. To learn more about Aging Skin & Wrinkles, explore our Anti-Aging Skin Care Products collection. A.G.E. Interrupter Advanced Sizes & Options 1 fl oz / 30 mL A.G.E. Interrupter Advanced Benefits Advanced anti-wrinkle cream for fine lines, deep wrinkles, and visible creases Clinically proven to help reverse collagen glycation by up to 33% 18% Proxylane helps improve the look of skin firmness, density, and elasticity 4.25% wild fruit flavonoids provide antioxidant support against visible free-radical damage Glycyrrhetinic acid helps improve the look of dullness and uneven tone 3% HEPES supports smoother texture and visible cell turnover 1% niacinamide helps support the moisture barrier and more even-looking skin Delivers 24-hour hydration with a rich, satin-finish texture Visibly improves wrinkle types across forehead wrinkles, crow’s feet, nasolabial folds, marionette lines, and glabellar lines Complements RF microneedling and collagen-remodeling procedures when cleared by your provider Clinical Proof 14% reduction in global fine lines 11.5% reduction in forehead wrinkles 11% reduction in nasolabial folds 7% reduction in marionette wrinkles 7% reduction in glabellar wrinkles 7% reduction in crow’s feet lines Helps reverse collagen glycation by up to 33% Recommended For Dry Combination Sensitive Normal Aging How to Use Apply A.G.E. Interrupter Advanced twice daily to clean, dry skin on the face, neck, and jawline. Massage gently using upward motions until fully absorbed. Follow with your preferred sunscreen during daytime use. Why It Works A.G.E. Interrupter Advanced uses Proxylane™ to support collagen integrity, while wild fruit flavonoids and glycyrrhetinic acid protect against oxidative stress and glycation. Niacinamide refines texture and tone, and HEPES helps renew surface cells for smoother, hydrated, and younger-looking skin. Ideal for mature or dry skin, this formula delivers lasting visible improvement in tone and firmness. FAQs Q1. Can A.G.E. Interrupter Advanced be used daily? A. Yes, apply morning and night for best anti-aging results. Q2. Is it suitable for sensitive skin? A. Yes, the formula is dermatologist-tested and non-irritating. Q3. How soon will results appear? A. Visible firmness and smoother texture can be seen within four weeks.
