Description Alarelin Acetate (GnRH agonist) is a single, non-glycosylated synthetic polypeptide chain containing 9 amino acids and has a molecular mass of 1167.3 Dalton. Summary Alarelin is a synthetic polypeptide which acts as LH-RH (Luteinizing-hormone releasing hormone) analogue agonist. LH-RH is secreted in the hypothalamus and its release induces the secretion of LH (luteinizing hormone) and FSH (Follicle-stimulating hormone) from the pituitary gland. These two hormones act on the ovaries and the testes and are responsible of the profertility effects of LHRH through the release of steroidal hormones. The biological activity of Alarelin, a synthetic LH-RH agonist, is dozens of times higher than that of LH-RH in the test of rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in the ovulation induction test. Other names Gonadotropin-releasing hormone (GnRH) superagonist, luteinizing hormone-releasing hormone agonist, luteinising hormone-releasing hormone agonist, GnRH agonist, LHRH agonist MOLECULAR FORMULA C56H78N16O12 x C2H4O2 Amino Acid Sequence 5-oxo-pro-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Nhet x CH3COOH. CAS REGISTRY NO. 79561-22-1 Type Synthetic peptide Purity Greater than 99.0%. Formulation Sterile-filtered white lyophilized (freeze-dried) powder. The Alarelin peptide was lyophilized with no additives. Reconstitution It is recommended to reconstitute the lyophilized Alarelin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. Shipping Shipped at ambient temperature. Upon receipt, store at the temperature recommended below. Storage/Expiration Lyophilized Alarelin, although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution, Alarelin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. Usage This product is intended for Laboratory Research Use Only. Not for use in diagnostic or therapeutic procedures. This product may not be used as a pharmaceutical or veterinary drug, agricultural product, or food additive. Resources Product Datasheet (PDS) Related Products Gonadotropin Hormones
