Pure Encapsulations Aller-Essentials Supports Healthy Immune Response to Environmental Factors Aller-Essentials contains a blend of nutrients and herbal extracts designed to maintain healthy seasonal immune function. EpiCor® Saccharomyces cerevisiae fermentate contains numerous immune-enhancing bioactive metabolites designed to support both innate and adaptive immune response. Research suggests that it enhances natural killer cell activation, B cell and T cell function, and salivary IgA levels. In a double-blind, placebo-controlled trial involving 96 subjects, EpiCor® supported nasal comfort during a 12-week period in the spring. Additionally, it supported salivary IgA levels, an important first-line defense produced by the mucosal tissue. In a randomized, double-blind trial involving 75 individuals, Tinospora cordifolia provided significant support for a healthy immune response by maintaining normal nasal function as well as healthy neutrophil and eosinophil activity. A randomized, double-blind, placebo-controlled trial involving apple polyphenols reveals support for maintaining a healthy nasal lining and nasal function. Quercetin, hesperidin, and vitamin C provide additional support for stabilizing mast cells. Key Benefits and Features: Ages 18 and up Environmental and seasonal immune response support Helps maintain healthy seasonal immune function Supports both innate and adaptive immune response Promotes normal nasal function Helps stabilize mast cells Made from a blend of nutrients and herbal extracts Made with high-quality ingredients backed by verifiable science Ingredients Serving Size: 2 Vegetarian Capsules Amount/Serving Vitamin C (as ascorbic acid) 250 mg Indian tinospora (Tinospora cordifolia) extract (aerial parts) 450 mg EpiCor dried yeast fermentate complex (from Saccharomyces ceravisae) 250 mg Quercetin 125 mg Hesperidin methyl chalcone 100 mg Apple (Malus pumila) extract (whole fruit) (standardized to contain 75% polyphenols) 50 mg Other Ingredients: Vegetarian capsule (cellulose, water), maltodextrin, ascorbyl palmitate. Does Not Contain: Wheat, soy, dairy, eggs, tree nuts, peanuts, gluten, artificial colors, flavors, sweeteners, coating, shellacs, GMOs, unnecessary binders, fillers, preservatives, magnesium stearate, trans fat, or hydrogenated oils. Non-GMO, Vegan, Vegetarian, Gluten-Free, Hypoallergenic Suggested Use As a dietary supplement, take 2 capsules, 1-2 times daily, with or between meals, or as directed by a health professional. Warning: If you are pregnant or lactating, have any health condition, or are taking any medication, consult your health professional before use. Storage: Store in a cool, dry place. More Info. Vitamin C is derived from corn dextrose fermentation Tinospora cordifolia extract is derived from roots and stems and standardized to contain 2.5% bitter principles Quercetin is derived from the Fava d’anta tree (Dimorphandra mollis) pods and Cat’s claw (Uncaria tormentosa) leaves Hesperidin methyl chalcone is derived from sweet orange EpiCor® dried yeast fermentate complex is derived from Saccharomyces cerevisiae Apple extract is derived from Malus pumila mill whole fruit and standardized to contain 75% polyphenols Maltodextrin is derived from corn Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil