Description Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria, including veterinary isolates of S. pseudintermedius, S. aureus, E. coli, Pasteurella, and S. canis (MIC50s = 0.25, 0.5, 2, 0.12, and 0.25 μg/ml, respectively). In vivo, ampicillin (80 mg/kg, i.v.) reduces cough frequency, tachypnea, dyspnea, and fever and increases survival in a baboon (P. cynocephalus) model of pneumococcal pneumonia. Formulations containing ampicillin have been used to treat a variety of bacterial infections. Specifications Total Product Size 25g Individual Container Size 25g Refrigeration Requirements Refrigerator Shipping Conditions ICE UNSPSC Code 51101500 UNSPSC Category Antibiotics and Antimycotics CAS [7177-48-2] Grade USP DG No Storage 2 to 8℃ Sterile Yes Application Ampicillin Trihydrate is commonly used to select for ampicillin resistance in mutated and transformed cells. Biochem/physiol Actions A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. Documents COA SDS Disclaimer: For laboratory research use only.
