Apiguard is an effective treatment against three common hive pests: Varroa mites, tracheal mites (Acarine), and chalkbrood. This natural treatment uses a slow-release thymol gel with an efficacy rate ranging from 85% to 95%, averaging 93% after thousands of treatments. It helps encourage the hygienic behavior of honey bees, preventing various related issues. Key Features: Natural, effective treatment for Varroa mites, tracheal mites, and chalkbrood. Efficacy rate of 85% to 95%, with an average of 93%. Ease of use: Two 50-gram treatment trays per hive, with an interval of 14 days. Best used in summer just after the honey flow, when temperatures are between 60°F and 105°F (15°C to 40°C). How to Use Apiguard: Place one treatment tray centrally on top of the brood frames, gel side up. Ensure at least 1/4 inch of spacing between the top of the tray and the hive cover by using HDO 1 1/4" spacer/shims or empty supers. After 14 days, apply the second dose. During treatment, keep screened bottom boards closed. Please note: This product is available for shipping to the contiguous 48 United States, excluding California. A shipping state must be selected before the item can be added to your cart.