Human anti-apoptotic cleavage product of human U1-70K antibody (20C4)

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Human anti-apoptotic cleavage product of human U1-70K antibody Antibody against the apoptotic cleavage product of human U1-70K. The U1-70K protein is specifically bound to stemloop I of the U1 small nuclear RNA contained in the U1 small nuclear ribonucleoprotein complex (U1 snRNP), which is involved in the splicing of pre-mRNA. All components of the U1 snRNP complex, including the U1-70K protein, are important autoantigens in patients with systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD) Show more