Ascorbic Acid for Interference Testing Catalog # K2010001A Lot # Batch Dependent Expiration Batch Dependent Volume 1 mL Appearance Clear solution Concentration 176 mg/mL (1.0 M) in Diluent A Molar Mass 176.12 g/mol Storage –20°C or lower; aliquot to avoid freeze-thaw Other Names Ascorbate, L-ascorbate, L-ascorbic acid This high-concentration ascorbic acid solution (1.0 M, 176 mg/mL) is formulated for interference testing in biochemical and clinical assay workflows. Supplied in 1 mL aliquots and stabilized in Diluent A, the clear solution enables researchers to simulate oxidative interference and assess assay robustness under physiologically relevant conditions. Ascorbic acid is a known interferent in colorimetric, enzymatic, and electrochemical platforms due to its redox activity and potential to scavenge reactive species. Applications include method validation, QC benchmarking, and interference panel construction. The solution is filtered for clarity and consistency, and should be aliquoted upon receipt to avoid repeated freeze-thaw cycles. This product is ideal for evaluating assay susceptibility to antioxidant interference and for developing mitigation strategies in diagnostic platforms. Key benefits: High-purity ascorbic acid solution for interference testing 1.0 M concentration enables robust spiking protocols Filtered and stabilized in Diluent A Supports colorimetric, enzymatic, and electrochemical platforms Stable at –20°C; aliquot recommended Indication for Use:This product is for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use. All Interference Products Brochure Download PDF References: Schiettecatte J et al. Interferences in Immunoassays. Adv Immunoassay Tech. 2012. Miller JJ, Levinson SS. Interferences In Immunoassays. Immunoassay. 1996;165–190. Ward G. Immunoassay interference investigations. Pathology. 2013;45. Park JY, Kricka LJ. Immunoassay interference. Immunoassay Handbook. 2013;403–416. EP07: Interference Testing in Clinical Chemistry. CLSI. 2020. Gilles A et al. Targeting the 80S ribosome in cancer. Cells. 2020;9(3):E629. Coussens NP et al. Assay interference in proximity assays. Assay Guidance Manual. 2020. Wang L et al. Fluorescent probes for nitric oxide. Org Biomol Chem. 2020;18(8):1522–1549. Kawasaki H et al. Drosophila GBA mutant phenotypes. Gene. 2017;614:49–55. Hull B. HAMA interference with TSH assay. J S C Med Assoc. 2012;108(1):12–13. Degn SE et al. Rat kappa light-chain interference. J Immunol Methods. 2011;372(1–2):204–8.
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