Assisi Loop Calmer Canine uses tPEMF technology to directly influence the amygdala, the part of the brain responsible for processing emotions. With the signal in Assisi Loop devices is designed to penetrate superficial tissues, Calmer Canine's signal is specially tailored to reach structures within the brain, safely modulating the emotional center of the brain in order to stimulate the release endorphins and promote a state of calm. How does it work? Put the vest on your dog Attach the device to the neck strap Turn the device on Treatment starts: Wait 15 minutes It will automatically turn off after 15 minutes Calmer Canine should be used twice a day for 15 minutes each time. Treatments should be spaced 8 to 10 hours apart. Delivery take 1 week 🚚 £3.95 Delivery 🌎 Worldwide ship