Product description Intensive Anti-Blemish Care for oily to blemish -prone skin, tested on 4600 individuals.Thanks to the Comedoclastin™** with patented properties, the new Comedomed+, now enriched with Niacinamide, has a global action to fight blemishes at the root. It reduces the appearance of blemishes, blackheads and post-acne marks with a 1-year* anti-reappearance relapse efficacy.The formula is concentrated in dermatological active ingredients with:- 25% Comedoclastin™**: with seboreducing activity, reduces blemishes.- 4% Niacinamide: improves the appearance of pores and reduces visible post-blemish marks.Enriched with soothing Avène Thermal Spring Water.A light gel-in-cream texture, moisturising and quickly absorbed with a non-greasy finish and non-comedogenic. Apply morning and night on a cleansed skin with a Cleanance hygiene product. Use alone or alongside with an anti-acne medication.*Limits the reappearance of imperfections. Clinical scoring, 2 applications a day for 12 months, 51 subjects.**Patent pending. Main benefits EFFECTIVE: On all types of blemishes, thanks to Comedoclastin™**, which limits the apperance of visible and invisble blemishes and prevent their reappearance.• FAST ACTION AND ANTI-REAPPEARANCE: Reduces blemishes in as little as seven days*. Prevents recurrence***. For clearer skin and improved comfort every day.• HIGH TOLERANCE: Used alone or in combination with drug treatments (excluding oral isotretinoin), its tolerance on sensitive, blemish-prone skin is clinically proven*. *Tolerance and efficacy study under dermatological control on 51 subjects, use of Cleanance Comedomed twice a day for 56 days.**Patent registered.***International clinical observational study, 90% of individuals without blemish reappearance at T6 months, (according to the definition of relapse in the GEA protocol ≥3 requiring the introduction of a drug treatment – oral or local), 48 subjects, two applications per day of Cleanance Comedomed for six months. How to use Advice for use: Spread 1 pump of Cleanance Comedomed on your fingertips, on a cleansed face.• Start by dabbing it onto the T-zone and the cheeks.• Use circular motions to boost penetration.• Finish by smoothing on the cheeks and lower face.It can be applied on a cleaned face, torso and back, morning and evening.