Specification Full name BCAR1 rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017] Swissprot No P56945 Gene Accession NP_001164185 WB Predicted band size 93 kDa WB Positive control WB Recommended dilution 1000-5000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human gastric cancer IHC Recommed dilution Recommended dilution: 50-200 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P109922-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or BCAR1 antigen-treated (Neutralization experiment) using P109922(BCAR1 Antibody) at dilution 1/50
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