Berberine is a naturally occurring alkaloid compound found in several plants including barberry (Berberis aristata), goldenseal, and tree turmeric. It has been the subject of extensive clinical research for its role in supporting metabolic health — including healthy blood glucose levels, cholesterol, triglycerides, and insulin sensitivity. Applied Nutrition Berberine provides a high-strength 1000mg of Berberine HCl per serving (2 capsules), enhanced with 35mg of AstraGin® — a patented absorption-enhancing compound derived from Astragalus and Panax Notoginseng — to maximise bioavailability.Applied Nutrition is a leading UK sports and nutrition brand listed on the London Stock Exchange (FTSE 250), producing science-based supplements formulated to rigorous quality standards. Products are manufactured in GMP-certified facilities and undergo independent testing for purity and potency. Supplement Facts Per serving (2 capsules) %NRV* Berberine HCl 97% (from Berberis aristata root) 1000 mg — AstraGin® (Astragalus membranaceus + Panax Notoginseng extract) 35 mg — *NRV = Nutrient Reference Value. — = NRV not established. Directions for use: Take 2 capsules daily with a main meal. Do not exceed the recommended dose. Consult a healthcare professional before use if pregnant, breastfeeding, diabetic, or taking any medication.Ingredients: Berberine Hydrochloride 97% (Berberis aristata), Bulking Agent (Microcrystalline Cellulose), AstraGin® (Astragalus membranaceus Extract and Panax Notoginseng Extract), Free-Flowing Agent (Magnesium Stearate), Capsule Shell (Hypromellose).FAQsWhat is berberine?Berberine is a bitter alkaloid compound found in barberry, goldenseal, and several other medicinal plants used across traditional Indian, Chinese, and European medicine. It is extensively studied for metabolic health, including glucose and lipid metabolism.What is AstraGin® and why is it included?AstraGin® is a patented compound combining Astragalus membranaceus and Panax Notoginseng extracts. It is clinically shown to enhance the absorption of a variety of nutrients, including berberine, by increasing intestinal transporter expression. Including AstraGin® in this formula helps maximise the amount of berberine that reaches the bloodstream.How does berberine work?Berberine activates AMPK (AMP-activated protein kinase), a central enzyme in energy balance and metabolism. This mechanism underpins its effects on glucose uptake, lipid synthesis, and metabolic rate regulation.Is this suitable for diabetics?Berberine can influence blood glucose levels. Those taking diabetes medication should consult a healthcare professional before use, as the combined effect may cause blood sugar to drop too low.Is this suitable for vegans?Yes — the capsule shell is Hypromellose (vegetable-derived) and the formula contains no animal-derived ingredients.
