Bio-Fisetin Benefits Maximizes fisetin bioavailability with special fenugreek fiber coating Helps your body clear senescent cells, supporting cellular health and longevity Supports brain health and helps protect brain function Supports healthy glucose metabolism, which helps protect eye and kidney health What Is Bio-Fisetin? Fisetin has loads of health benefits. But fisetin is rapidly metabolized during the digestive process. So we’ve created a formula that helps preserve fisetin, so you get the maximum benefit. We’ve combined fisetin with special galactomannan compounds from fenugreek seeds. Doing so protects fisetin during digestion, a technique we pioneered with our flagship Curcumin Elite™ formula. The result: better bioavailability—up to 25 times better than unformulated fisetin—so your body gets the maximum health benefits. Most forms of fisetin have low bioavailability, but not Bio-Fisetin—thanks to special fenugreek fibers called galactomannans. Making a more bioavailable fisetin When you ingest fisetin, enzymes in your digestive system soon break it down to various metabolites. To shield it from being quickly broken down, we’ve combined fisetin with galactomannan fibers from fenugreek seeds, a technique we pioneered with our Curcumin Elite™ formula. Doing so preserves fisetin through your digestive system, allowing it to circulate: Bio-Fisetin is up to 25 times more bioavailable than standard fisetin supplements. Why Should I Supplement with Bio-Fisetin? Have you ever thought about supporting your health and youthfulness at the cellular level? It's possible, and better yet, we know one of the secrets: fisetin. Found in fruits and vegetables, fisetin is an antioxidant that encourages the natural clearing of senescent cells. You know, the ones that have outlived their usefulness. But, it's hard for the body to absorb. That's why Life Extension’s experts optimized our Bio-Fisetin formula to be up to 25 times more bioavailable. That means it circulates in your body longer, so you're getting the maximum benefits. What are those benefits? Fisetin supports your brain health, cellular health, longevity and more. Optimize your health support at the cellular level with Bio-Fisetin from Life Extension. Product Details By combining fisetin with fenugreek fibers, we’re able to create a fisetin formula that is up to 25 times more bioavailable. This means that the fisetin in our Bio-Fisetin supplement circulates longer than traditional fisetin. So what good can all that extra time with fisetin do for your body? As it turns out, quite a bit! Fisetin and cellular senescence Cellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them. Fortunately, fisetin is a senolytic compound—an ingredient that actively targets senescent cells. In fact, fisetin is among the strongest senolytic compounds discovered so far. Fisetin helps encourage the body’s natural pathways for clearing senescent cells, which allows healthy cells to flourish.1 Another important aspect of cellular longevity is sirtuin function. Sirtuin proteins keep your cells performing at their best—but sirtuin activity declines with age. Fisetin has been shown in preclinical studies to encourage youthful, healthy sirtuin function.2-6 Fisetin and brain health Protecting your brain is another good way to live longer. A recent clinical trial showed that fisetin helped protect the delicate nerve cells in the brain, and it has also shown promise for encouraging healthy cognitive function in preclinical studies.7-9 The key is absorbing enough fisetin for it to matter. Fisetin and glucose metabolism Glucose metabolism is important for everything from kidney function to how your body gains or loses weight. But maintaining already-healthy blood sugar can get harder as we get older. Studies indicate that fisetin acts as a kind of metabolism control switch, which may help your body maintain healthy glucose levels already within normal range.10,11 This in turn helps promote kidney health and vision health.
