BioSkryb ResolveDNA Library Prep Kit Description The BioSkryb ResolveDNA Library Prep Kit is designed for high-resolution genomic analysis, enabling the preparation of high-quality libraries from limited starting material. This kit utilizes Primary Template-Directed Amplification (PTA) technology to provide uniform coverage across the genome, which is essential for identifying single nucleotide variants and copy number variations with high sensitivity. Key Features Utilises Primary Template-Directed Amplification (PTA) to ensure high genomic coverage and uniformity. Minimises amplification bias compared to traditional whole genome amplification methods. Enables high-fidelity sequencing results suitable for detecting low-frequency variants. Streamlined workflow designed for efficient library construction from amplified DNA. Compatible with standard downstream next-generation sequencing (NGS) platforms. Applications Single-cell whole genome sequencing (WGS) Oncology research and somatic mutation profiling Preimplantation genetic testing and rare cell analysis Genomic heterogeneity studies in complex biological samples Specifications Amplification Technology: Primary Template-Directed Amplification (PTA) Target Input: Low-input DNA or single-cell lysates Downstream Compatibility: Next-Generation Sequencing (NGS) platforms Application Focus: Whole Genome Sequencing (WGS) Disclaimer Users should ensure their specific sequencing platform and bioinformatics pipeline are compatible with PTA-based library structures.
