Biote NAD+ 300 is a professional-grade nutraceutical supplement delivering 300 mg of nicotinamide riboside (NR) per capsule — a patented form of vitamin B₃ and a direct precursor to NAD+ (nicotinamide adenine dinucleotide). Biote+2Cunningham Clinic+2 Why it matters: NAD+ is a vital coenzyme present in every cell, playing a central role in cellular energy production, DNA repair, and metabolic regulation. happyhormonesmd.com+2Healthline+2 Unfortunately, NAD+ levels naturally decline with age — studies suggest this drop can be as much as 50–65% between young adulthood and roughly age 70. By supplying NR, Biote NAD+ 300 helps restore and sustain NAD+ levels, supporting healthy mitochondrial function and overall cellular health.