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BLVRB rabbit polyclonal antibody
USD 154.00
Biofargo
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Specification Full name BLVRB rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal T
arget Background BLVRB (biliverdin reductase B or BVR-B), also known as flavin reductase (FR), NADPH-dependent diaphorase, Biliverdin-IX ∫-reductase or green heme-binding protien (GHBP) is an enzyme involved in fetal heme metabolism. It is dependent on NADPH and is responsible for catalyzing the transfer of electrons to flavins from reduced pyridine nucleotides. BLVRB exists as a monomer, localizes to the cytoplasm and is highly expressed in fetal liver and adult erythrocytes and, to a lesser extent, in heart, lung, cerebrum and adrenal gland. In liver, BLVRB functions to convert biliverdin (isoforms IX∫, IX© and IX∂) to bilirubin. BLVRB contains one binding site for all of its substrates and predominantly interacts with them through hydrophobic interactions. BLVRB also exhibits ferric reductase activity. In addition, it is commonly used as a reliable marker for NOS. Swissprot No P30043 Gene Accession NP_000704 WB Predicted band size 22 kDa WB Positive control WB Recommended dilution 500-2000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human tonsil IHC Recommed dilution Recommended dilution: 40-200 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P103297-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or BLVRB antigen-treated (Neutralization experiment) using P103297(BLVRB Antibody) at dilution 1/65
