Product Details What is HMB Supplement? HMB (beta-hydroxy beta-methylbutyrate) is a highly bioavailable metabolite of leucine, a branched-chain amino acid (BCAA) that is essential for protein synthesis and muscle repair. Calcium HMB is a calcium salt form of HMB that reduces muscle protein breakdown. The body can synthesize HMB while metabolizing leucine, but it does so in very small amounts. Clinical studies have shown that calcium HMB supplements can significantly reduce muscle fatigue and the catabolic breakdown of muscle tissue that accompanies strenuous exercise, intense bodybuilding workouts, or muscle trauma. Potential HMB Benefits Calcium HMB Supplement for Exercise Performance HMB is a popular ergogenic supplement that enhances athleticism. Numerous studies have examined HMB’s effects on exercise performance. Clinical trials have reported that healthy adults taking HMB supplements experience improvements in muscle gain from exercise, overall strength, and lean body mass. Calcium HMB is an anti-catabolic compound that inhibits the breakdown of muscle proteins. On a gram-per-gram basis, HMB dramatically outperforms leucine as an anti-catabolic agent. Athletes may benefit from this in several ways. For example, athletes often consume calorie-restricted diets following a bulking phase. However, the body doesn’t limit weight loss to fat. It can also target muscle tissue, but taking an anti-catabolic like calcium HMB can preserve muscle mass. A 12-week clinical trial showed that calcium HMB improved aerobic exercise capacity and anaerobic power—the max amount of power an individual can exert when performing high-intensity workouts—compared to a placebo. Researchers also noted a reduction in body fat. A different 12-week study reported similar findings with significant increases in aerobic and anaerobic exercise capacity compared to the placebo group. Both studies focused on highly trained athletes and imply calcium HMB has the potential to improve exercise adaptation in the long term. Calcium HMB Synergy Calcium HMB supplement synergizes with several other supplements. HMB + Creatine One study found that combining HMB with creatine produced significant improvements in strength and exercise performance during high-intensity workouts. HMB and Vitamin D Multiple studies reported that a combination of HMB with vitamin D increased muscle strength in older adults. Some participants experienced this benefit without exercising. Calcium HMB Supplement for Muscle Damage and Recovery Athletes and fitness enthusiasts put their bodies through a lot to gain muscle. Muscle injuries, although unwanted, are common. Muscle soreness is also typical following intense exercise. Scientific studies show that HMB supplements dramatically reduce muscle damage markers and promote better recovery. They also reduce markers of inflammation. Potential HMB Side Effects HMB supplements are likely safe for most individuals, as HMB is a metabolite of leucine—an essential amino acid that the body needs to sustain life. Rarely, some people may experience HMB side effects like constipation, stomachache, or itching. References https://pubmed.ncbi.nlm.nih.gov/23551944 https://pubmed.ncbi.nlm.nih.gov/24057808 https://pubmed.ncbi.nlm.nih.gov/26169182 https://academic.oup.com/ajcn/article/109/4/1119/5455602 https://pubmed.ncbi.nlm.nih.gov/26225130 https://pubmed.ncbi.nlm.nih.gov/11128859 https://pubmed.ncbi.nlm.nih.gov/8941534 https://pubmed.ncbi.nlm.nih.gov/10978853 https://pubmed.ncbi.nlm.nih.gov/11448573 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566641 https://pubmed.ncbi.nlm.nih.gov/23514626 https://pubmed.ncbi.nlm.nih.gov/20460233 https://pubmed.ncbi.nlm.nih.gov/28708126 https://pubmed.ncbi.nlm.nih.gov/26849784 https://pubmed.ncbi.nlm.nih.gov/17469236 https://pubmed.ncbi.nlm.nih.gov/24782684 https://pubmed.ncbi.nlm.nih.gov/29037326 https://pubmed.ncbi.nlm.nih.gov/27188901 https://pubmed.ncbi.nlm.nih.gov/30804112 https://pubmed.ncbi.nlm.nih.gov/31635165 https://pubmed.ncbi.nlm.nih.gov/26000306 https://pubmed.ncbi.nlm.nih.gov/26965178 https://pubmed.ncbi.nlm.nih.gov/32857128 https://pubmed.ncbi.nlm.nih.gov/15080599 https://pubmed.ncbi.nlm.nih.gov/11128860 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568064 https://pubmed.ncbi.nlm.nih.gov/25663250 https://pubmed.ncbi.nlm.nih.gov/24279396 https://pubmed.ncbi.nlm.nih.gov/29676656 https://pubmed.ncbi.nlm.nih.gov/28554316 https://academic.oup.com/biomedgerontology/article/75/11/2089/5898559 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882564 https://www.sciencedirect.com/science/article/pii/S0261561417313560
