CALIBRAE™ PREP OPTIMIZER – Epicutis Hydrobiome Mist (50 mL) A lightweight hydration support step designed to reinforce the skin barrier, balance the microbiome, and improve overall skin comfort throughout the day. WHAT IT DOES Delivers immediate hydration while supporting the skin’s natural microbiome and barrier function. WHY IT MATTERS Hydration is often misunderstood as a one-time step. In reality, skin loses water continuously throughout the day due to: environmental exposuretemperature changesair qualitybarrier disruption When hydration drops: skin becomes reactiveinflammation increasesbarrier function weakensresults become inconsistent This formulation provides a fine, breathable layer of hydration that can be reapplied without disrupting the routine. By supporting the microbiome and reinforcing the barrier, it helps maintain skin stability between core treatment steps. The result:skin that stays balanced, calm, and hydrated throughout the day CLINICAL POSITIONING This is not a replacement for barrier repair. It is a support step used to maintain hydration and skin comfort between primary applications. It is especially useful for: sensitive skinpost-procedure supportdry environmentsfrequent travelincreased skin reactivity Used correctly, it improves consistency without adding complexity. HOW TO USE AM / PM — OPTIONAL SUPPORT STEP → Mist lightly over skin after cleansing or throughout the day→ Allow to absorb naturally→ Can be reapplied as needed Follow with:→ Barrier Serum→ Additional steps based on routine CALIBRAE™ SYSTEM PLACEMENT PHASE 4 — OPTIMIZE Used to support hydration, barrier function, and overall skin stability once a core routine is established. This step enhances consistency but does not replace foundational products. Part of the Calibrae™ Layer Method™Protect → Correct → Build SIZE 50 mL