Ortho Molecular Cardio B Cardiovascular Health Cardio B uses high doses of folic acid, B12, B6, and trimethylglycine (betaine) to support homocysteine balance. Methylation is a vitamin-requiring biochemical process in the body that is critical for maintaining mental and physical health. Methylation helps convert the problematic amino acid metabolite homocysteine into the amino acids methionine and cysteine. Consistent recycling of homocysteine is vital for supporting cardiovascular health. Proper methylation can be inhibited by nutrient deficiencies, especially of folic acid, B6, and B12. Certain medications, such as acetaminophen, aspirin, ibuprofen, and oral contraceptives, can also deplete blood levels of these crucial B vitamins, reducing the body's vital methylation capacity. Cardio B contains targeted amounts of folic acid, B12, B6, and betaine (trimethylglycine) to support methylation pathways in the body. Key Benefits and Features: Supports Cardiovascular and Neurologic Health Supports Homocysteine Balance Supports Healthy Arterial Function Maintains Normal Inflammatory Balance Ingredients Serving Size: 1 Capsule Amount/Serving Vitamin B6 (as Pyridoxine Hydrochloride USP) 50 mg Folate (5,000 mcg Folic Acid) 8,500 mcg DFE Vitamin B12 (as Methylcobalamin) 1,000 mcg Betaine (Trimethylglycine) 500 mg Other Ingredients: None. Does Not Contain: Gluten, corn, yeast, artificial colors or flavors. Suggested Use Take 1 or more capsules per day or as recommended by your health care professional. Warning: If you are pregnant or nursing, consult your physician before taking this product. Keep out of the reach of children. Storage: Keep tightly closed in a cool, dry place. More Info. Folate Adequate folate status is critical for maintaining optimal methylation, red blood cell balance, DNA and RNA synthesis, and healthy cell division and replication. Folic acid is converted into its metabolically active form, 5-MTHF, by the enzyme methylenetetrahydrofolate reductase (5-MTHFR). 5-MTHF donates its methyl group to vitamin B12 (cobalamin), forming methylcobalamin. Methylcobalamin helps convert the problematic amino acid metabolite homocysteine into the amino acid methionine. B12 Vitamin B12 (methylcobalamin) works along with folic acid in many body processes, including the synthesis of DNA, red blood cells, and supporting the health of the myelin sheath, the insulating exterior that surrounds nerve cells. B12 is found primarily in animal foods. Vegetarians and the elderly are at the highest risk for B12 deficiency. B12 is considered by many to be a vital nutrient required to balance homocysteine levels. Methylcobalamin is the biologically active form of B12 and supports upregulation of methylation pathways. B6 Vitamin B6 (pyridoxine) is a B vitamin that is required for more than 60 different enzymatic reactions that occur in the body. Vitamin B6 works along with folic acid and B12 for the recycling of homocysteine. B6 also supports a healthy cardiovascular system by promoting healthy platelet aggregation and aids in maintaining healthy blood pressure. Vitamin B6 is required for the activation of lysyl oxidase, an enzyme responsible for the cross-linking of collagen and elastin, which is crucial for maintaining normal circulation and arterial function. Trimethylglycine (Betaine) Trimethylglycine (betaine) functions in the body as a unique methyl donor, supporting liver function and detoxification pathways and the conversion of homocysteine to methionine. Trimethylglycine also works alongside B6, B12, and folic acid in supporting homocysteine balance.
