Caspase-1 Substrate VI Fluorogenic Catalog number: B2014021 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 2 mg Molecular Weight or Concentration: 719.66 g/mol Supplied as: Powder Applications: molecular tool for various biochemical applications Storage: −20°C Keywords: Caspase-1 Substrate VI, Fluorogenic Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Wang Q, Ju X, Chen L, Chen K. Caspase-1 from the silkworm, Bombyx mori, is involved in Bombyx mori nucleopolyhedrovirus infection Z Naturforsch C J Biosci. 2017 Mar 1;72(3-4):147-153. Yang G, Wang J, Luo T, Zhang X. White spot syndrome virus infection activates Caspase 1-mediated cell death in crustacean Virology. 2019 Feb;528:37-47. Yang Z, Zhou K, Liu H, Wu A, Mei L, Liu Q. SfDredd, a Novel Initiator Caspase Possessing Activity on Effector Caspase Substrates in Spodoptera frugiperda PLoS One. 2016 Mar 15;11(3):e0151016. Gastaldello S, Chen X, Callegari S, Masucci MG. Caspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells PLoS Pathog. 2013;9(10):e1003664. Lu J, Sun PD. High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity J Biol Chem. 2020 Dec 25;295(52):18579-18588. Guy MP, Friesen PD. Reactive-site cleavage residues confer target specificity to baculovirus P49, a dimeric member of the P35 family of caspase inhibitors J Virol. 2008 Aug;82(15):7504-14. Duval R, Delebasse S, Cardot PJ, Bosgiraud C. Visna virus-induced cytopathic effect in vitro is caused by apoptosis Arch Virol. 2002 May;147(5):943-59. Huang Hk, Joazeiro CA, Bonfoco E, Kamada S, Leverson JD, Hunter T. The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7 J Biol Chem. 2000 Sep 1;275(35):26661-4. Chiou SK, White E. Inhibition of ICE-like proteases inhibits apoptosis and increases virus production during adenovirus infection Virology. 1998 Apr 25;244(1):108-18.