Stimulates cellular antioxidant defences within the body Broccoli sprouts may activate key enzymes in liver detoxification Scientific research indicates that selenium supports antioxidant activity in the body Broccoli sprouts when produced according to Cell-Logic’s proprietary Australian technology are a highly-concentrated source of Broccoli phytonutrients. The benefits of Broccoli in the human diet are well-known. EnduraCell Plus® combines 100% Whole Broccoli Sprout powder with a natural source of selen-ium. Selenium is a trace element which is associated with the production of cell-protective com-pounds activated by broccoli phytonutrients. EnduraCell Plus® does not contain goitrogens or significant levels of Vitamin K. Application Adults: Take 1– 3 capsules twice daily or as directed by your Health Care Practitioner Warnings This product contains selenium which is toxic in high doses. For adults, a daily dose of 150 mi-crograms of selenium from dietary supplements should not be exceeded. Do not exceed 6 capsules daily. Store below 30°C away from light and moisture. Very occasionally, gastro-intestinal adverse effects have been reported, and include nausea, gastro-abdominal discomfort and diarrhoea. Limited data available seem to indicate that such effects are limited to certain pre-existing gastro-intestinal conditions, in particular, those with dysbiosis. However, it has been observed that for those affected, the dose can be managed in a manner whereby the symptoms disappear and may not recur even after the consumption of larger doses. Evidence Li D et al. Synergy between broccoli sprout extract and selenium in the upregulation of thioredoxin reductase in human hepatocytes Food Chemistry 110 (2008) 193–198 Lee J-M, Johnson JA. An Important Role of Nrf2-ARE Pathway in the Cellular Defense Mechanism Journal of Biochemistry and Molecular Biology 2004 ; 37(2):139-143 Fahey JW, Talalay P. Antioxidant Functions of Sulforaphane: a Potent Inducer of Phase II Detoxication Enzymes. Food and Chemical Toxicology. 1999; 37:973-979 Fahey JW, Kensler TW. Role of dietary supplements/nutraceuticals in chemoprevention through induction of cytoprotective enzymes. Chem Res Toxicol. 2007 Apr;20(4):572-6. Yeh C-T, Yen G-C. Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells. Carcinogenesis 2005;26 (12) ;2138–2148 Jeong W-S et al. Modulatory Properties of Various Natural Chemopreventive Agents on the Activation of NF-κB Signaling Pathway. Pharmaceutical Research. 2004;21(4): 661-670. Innmorato NG et al. The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation. The Journal of Immunology 2008;181:680 – 689. Wu L, Juurlink B The impaired glutathione system and its up-regulation by sulforaphane in vascular smooth muscle cells from spontaneously hypertensive rats. Journal of Hypertension 2001, 19:181-1825 Cramer J, Jeffery EH. Sulforaphane Absorption and Excretion Following Ingestion of a Semi-Purified Broccoli Powder Rich in Glucoraphanin and Broccoli Sprouts in Healthy Men.2011; Nutrition and Cancer, 63(2), 196–201 Halliwell B Free radicals and antioxidants – quo vadis? Trends in Pharmacological Sciences 2011: 32(3):125-130. Kensler TW et al. Translational Strategies for cancer prevention in liver. Nature Reviews Cancer 3, 321-329 (May 2003) 2001 Steinkellner H et al. Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens. Mutation Research 480–481 (2001) 285–297. Nutritional Information Each capsule contains: EnduraCell® 100% Whole Broccoli Sprout Powder (Brassica oleracea var. italica sprout powder) 700mg Selenomethionine (delivering 25 mcg selenium) 62.5mcg NOTE: Cell-Logic EnduraCell® is hydroganically grown in a carefully controlled environment to maximise bioactivity. Our hydrogranic growing process does not use any herbicides, pesticides or other harmful chemicals. EnduraCell Plus® is GMO free.
