The corner of the eye, where it shows first.Where skin creases when you smile and, lately, stays creased a moment longer.MossCellTec™ No. 1 sits here at 2% — exactly the level its own studies used. Measured against placebo over 28 days, the appearance of crow's-feet wrinkle depth fell 15%. And in the most punishing test in its file — 23 women through a Seoul summer, moving between outdoor heat and dry air-conditioned offices — every one of the 23 recorded a significant increase in skin hydration on the treated side within 14 days, and 91% recorded lower water loss. That is a responder rate inside one clinical cohort, not a guarantee.DNA Gel PH™ at 5.00% — high-purity polynucleotides from salmon soft roe, fragmented to around 110 kDa. Five per cent is the maximum concentration its supplier has ever tested. Watch the units when you shop this category: competitors print figures like "10,000 ppm", which sounds enormous and is one per cent of a raw solution. Our 5% delivers 1,500 ppm of polymerised sodium DNA into the finished serum. In the supplier's evaluation on 10 volunteers over 8 days, it produced a significant increase in mechanical elasticity and suppleness.PhytoCellTec™ Malus Domestica was the first plant stem cell active in cosmetics, and it is patented in five countries. In its maker's four-week trial with 20 subjects, a 2% cream applied twice daily to the crow's feet area reduced wrinkle depth by 8% at two weeks and 15% at four, measured by the PRIMOS system.One number here does not flatter us: PhytoCellTec™ sits at 1% where that study used 2%. We print it anyway, and it rises on the next production run. The clinical weight in this formula is carried by MossCellTec™ at 2% and DNA Gel PH™ at 5% — both at, or at the top of, their studied concentrations.Applied at night. Made in Carros, France. The research is Mibelle Biochemistry's and Sederma's own, into the ingredients rather than into this finished serum.Contains fish. The polynucleotide complex is salmon-derived, so this serum is not vegan and is not suitable for anyone with a fish allergy. Patch test 48 hours before first use. For external use only. Avoid the eye area. Results refer to the appearance of skin and vary between individuals.
