Ortho Molecular Cerenity Endocrine Health Cerenity includes advanced neurotransmitter support to fight stress and promote relaxation. Neurotransmitters are the chemical messengers that regulate mood, memory, sleep cycle and daily stress. Adequate neurotransmitter production depends on an adequate supply of amino acids, vitamins and minerals in the diet. Cerenity® is a comprehensive formula designed to address daily stress by increasing the production of the calming neurotransmitters serotonin and gamma-amino butyric acid (GABA). Cerenity® also includes key ingredients that quickly increase the production of alpha brain waves resulting in a relaxed and effortless state of alertness. Key Benefits and Features: Supports a State of Calmness and Relaxation Increases Serotonin and GABA production in the Brain Addresses Neurotransmitter Signaling Systems Supports Occasional Sleeplessness Ingredients Serving Size: 3 Capsules Amount/Serving Vitamin C (as Ascorbic Acid USP) 50 mg Niacin (as Niacinamide USP) 10 mg Vitamin B6 (as Pyridoxal 5'-Phosphate) 10 mg Folate (from 400 mcg as Quatrefolic (6S)-5-Methyltetrahydrofolic acid glucosamine salt) 680 mcg DFE Vitamin B12 (as Methylcobalamin) 200 mcg Magnesium (as DiMagnesium Malate) 75 mg Zinc (as TRAACS Zinc Bisglycinate Chelate) 5 mg Inositol NF 1 g Taurine USP 300 mg L-Theanine (Suntheanine) 100 mg Gamma Aminobutyric Acid (PharmaGABA) 100 mg 5-Hydroxytryptophan (5-HTP) (from Griffonia simplicifolia (Seed)) 75 mg Other Ingredients: None. Does Not Contain: Wheat, gluten, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, or preservatives. Suggested Use Take 3 capsules taken 1-3 times per day or as recommended by your health care professional. Warning: If you are pregnant, nursing, or taking any medications for depression or anxiety, consult your healthcare provider before taking this product. Keep out of the reach of children. Storage: Keep tightly closed in a cool, dry place. More Info. L-Theanine L-theanine is an amino acid found abundantly in green tea. L-theanine has been shown to quickly improve stress perception and resilience. The stress-buffering mechanisms of L-theanine have been connected to its ability to increase serotonin and dopamine production in the brain. L-theanine has also been shown to significantly increase alpha brain wave activity, which is critical for increasing attention as well as promoting a sense of relaxation. In a study on healthy volunteers, electroencephalograph (EEG) readings of participants were recorded following the ingestion of 50 mg of L-theanine. The researchers found a greater increase in alpha brain wave activity versus placebo. L-theanine has also been shown to have a protective effect on nerve cells overstimulated by the excitatory neurotransmitter glutamate. PharmaGABATM Gamma-amino butyric acid (GABA) is one of the major inhibitory neurotransmitters in the brain. GABA provides a calming effect and is a primary component of the body’s stress-fighting mechanisms. GABA is also available as a dietary supplement. Cerenity® includes a patented, naturally sourced, nonsynthetic form of GABA called PharmaGABATM. It is produced naturally by the friendly bacteria, Lactobacillus hilgardii. PharmaGABATM has been shown in published research studies to promote relaxation effects in the central nervous system (CNS). In a double-blind study using healthy volunteers, EEG readings were obtained after 100 mg of PharmaGABATM was administered. PharmaGABATM produced a highly significant increase in alpha waves, as well as a significant decrease in beta waves, when compared to the control group. Alpha brain waves are associated with relaxed and effortless focus, while beta waves are associated with stress, restlessness, and scattered thoughts. Therefore, an increase in alpha to beta waves is associated with improved concentration and a state of centered relaxation. Inositol Inositol is a B vitamin that is an important component of cell membrane signaling. As part of the cellular signaling system of the CNS, inositol is crucial for the release of neurotransmitters from within the nerve cells. A deficiency of inositol can affect brain signaling, resulting in inadequate neurotransmitter release, causing irritability, worry, and restlessness. Taurine Taurine is an amino acid that is found abundantly in the brain and has neuroprotective properties. Taurine promotes inhibitory neurotransmission due to its ability to activate GABA receptors. Taurine also supports inhibitory neurotransmission by activating glycine receptors in the brain. 5-HTP 5-hydroxytryptophan (5-HTP) is an amino acid intermediate that is directly converted into the mood-regulating neurotransmitter serotonin. Maintaining a healthy serotonin level is important for regulating appetite and the sleep cycle and for supporting a sense of calmness. As a dietary supplement, 5-HTP is produced naturally from the seeds of the African plant, Griffonia simplifolia. In contrast to L-tryptophan, 5-HTP provides efficient conversion into serotonin because it does not need prior conversion by tryptophan hydroxylase. Micronutrients Cerenity® includes essential nutrients that are required for the synthesis of serotonin and GABA neurotransmitters. This includes 5-methyltetrahydrofolate (5-MTHF), vitamin B6 (P-5-P), vitamin C, zinc, and magnesium. 5-MTHF is the biologically active form of the B vitamin folic acid, which is vital for supporting proper mood regulation. 5-MTHF works together with B12 as a methyl group donor. Methyl (CH3 ) group donation is important for maintaining neurotransmitter synthesis. Magnesium is a mineral that calms the nervous system by binding to glutamate receptors, which reduces excitatory neurotransmitter activity. The combination of the minerals zinc and magnesium helps reduce glutamate to non-toxic levels, providing significant neuroprotection.
