Ciprofloxacin Tablets, 750mg

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High-Dose Fluoroquinolone Antibiotic Tablets for Serious Bacterial Infections in Large Pets Product Description Ciprofloxacin 750mg Tablets are a prescription fluoroquinolone antib iotic used by veterinarians for large dogs, horses, and occasionally cats dealing with serious bacterial infections. It goes after the bacterial enzymes DNA gyrase and topoisomerase IV, both of which the bacteria need to replicate their chromosomes and divide. Taking those enzymes out of the picture stops replication and drives the organisms rapidly toward cell death. The 750mg strength is the highest available oral concentration and suits giant breed dogs needing the maximum weight-based fluoroquinolone dose in one tablet. Used entirely off-label and never in food-producing animals. Benefits Giant Breed Dose Convenience: Delivers the highest single-tablet ciprofloxacin dose available, making it the practical fit for giant breed dogs needing the maximum weight-based fluoroquinolone amount. Serious Infection Coverage: Brought in when higher-dose fluoroquinolone therapy is what deep-seated, severe, or difficult-to-treat bacterial infections call for. Urinary and Kidney Infection Treatment: Builds up high urinary concentrations that work effectively against susceptible bacteria behind kidney and urinary tract infections. Broad Gram-Negative Coverage: Highly active against a broad range of gram-negative organisms commonly tied to serious systemic infections in dogs and horses. Resistant Infection Alternative: Used when culture results confirm susceptibility and other first-line antibiotics have not been able to clear the bacterial infection. Ingredients Active Ingredients Ciprofloxacin Hydrochloride 750mg How to Use Ciprofloxacin 750mg Tablets are a prescription-only medication. A valid veterinarian prescription is required to purchase this product. Please follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet. Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet. Tucking the tablet into a soft pill pocket or pill wrap treat is a practical way to make sure large dogs take and swallow their full dose. Shop Pill Pockets for Dogs Additional Information Precautions Not for Young or Growing Animals: Dogs under one year, kittens, and large breed dogs under two years should not receive this medication due to serious cartilage damage risk in developing joints. Not for Food-Producing Animals: The FDA strictly prohibits ciprofloxacin in animals destined for human food consumption and it should never be used in livestock or poultry. Extreme Caution in Cats: Cats, particularly those with pre-existing kidney compromise, carry a significantly elevated risk of adverse effects and need very careful veterinary management on this medication. Avoid in Pregnancy and Breeding: Pregnant, lactating, or breeding animals should not receive this medication due to the risk of cartilage damage in developing offspring. Avoid Antacids and Mineral Products: Antacids, sucralfate, iron, aluminum, dairy, and calcium products should all be spaced at least two hours away from each ciprofloxacin dose. Caution in Seizure Disorders: Animals with a known epilepsy or CNS disorder history need very careful management, as fluoroquinolones can bring the seizure threshold down. Drug Interaction Risk: Share a full list of your pet's current medications, including theophylline, warfarin, cyclosporine, probenecid, NSAIDs, and insulin, with your veterinarian before starting treatment. Possible Side Effects Gastrointestinal Upset: Diarrhea, loose stools, vomiting, and nausea are among the more commonly seen reactions and tend to be mild in most dogs. Joint Cartilage Damage: In young and growing animals, fluoroquinolone use can cause irreversible erosive cartilage lesions that lead to lameness and joint disease. Elevated Liver Enzymes: Abnormal liver enzyme values can come up and are more likely to be caught with periodic bloodwork during longer treatment courses. Neurological Signs: Rare CNS effects including tremors and seizures are serious and need immediate emergency veterinary care if they appear during treatment. Serious Allergic Reactions: Hives, facial or throat swelling, trouble breathing, or sudden collapse all point to a severe reaction needing immediate emergency care. Storage Information Room Temperature: Tablets do best at room temperature inside a tightly closed container, kept away from heat and humidity. Protect From Light and Moisture: Direct sunlight and damp conditions can wear down the tablet's potency, so a dry, shaded storage spot is the right choice. Out of Reach: Keep this medication somewhere children and untreated animals in the home cannot get to it. NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial. Shipping & Return We offer ground, express, and priority delivery; see our shipping policy for details. For return instructions or product concerns, please refer to our detailed refund policy. Prescription items are NON-RETURNABLE and NON-REFUNDABLE. Frequently Asked Questions Q1: When would a veterinarian choose ciprofloxacin 750mg over lower-strength tablets for a dog? Ans: Giant breed dogs needing the maximum weight-based fluoroquinolone dose in a single tablet are the most obvious fit for the 750mg strength, since it removes the need to stack multiple lower-strength tablets. Dogs with severe or deep-seated infections where hitting maximum tissue concentrations matters may also be a good candidate. A veterinarian will work out the exact dose from the dog's body weight. Q2: Is culture and sensitivity testing required before prescribing ciprofloxacin for dogs? Ans: Testing is not always done before starting but is strongly recommended for serious or recurring infections where getting the choice right matters most. It confirms which organisms are present and whether ciprofloxacin will actually work against them. With fluoroquinolone resistance on the rise, locking in susceptibility before committing to treatment is the more reliable approach. Q3: Why is ciprofloxacin considered an alternative rather than a first-line veterinary antibiotic? Ans: Without FDA veterinary approval and with less predictable oral absorption in dogs than the approved alternative enrofloxacin, ciprofloxacin sits further down the prescribing hierarchy. Veterinary guidelines also push toward keeping fluoroquinolones in reserve for cases where culture confirms susceptibility and other antibiotic classes have already been considered. A veterinarian will reach for it only when the clinical picture genuinely calls for it. Q4: What theophylline interaction should owners know about when their dog takes ciprofloxacin? Ans: Ciprofloxacin slows the liver's breakdown of theophylline, pushing its blood concentration higher than the prescribed dose was meant to achieve. Dogs on theophylline for conditions like bronchitis or tracheal collapse can tip into toxicity, with seizures, vomiting, a racing heart, and agitation among the signs. Letting a veterinarian know about theophylline before starting ciprofloxacin is essential. Q5: Can ciprofloxacin 750mg tablets be split for medium-sized dogs? Ans: Splitting is an option when a veterinarian has determined that a portion of the tablet is the right dose for the dog's weight. A tablet splitter gives a cleaner and more accurate cut than trying to break it by hand. Checking with the veterinarian before making any changes to the tablet is important since the dose is calculated precisely around body weight and the infection being treated. Show more