CJC-1295 (No DAC) is a synthetic 29-amino acid analogue of endogenous growth hormone-releasing hormone (GHRH 1-29), engineered with targeted amino acid substitutions studied for their effect on receptor binding affinity and resistance to enzymatic degradation. Supplied as a lyophilized powder in a sealed laboratory-grade glass vial. Intended for in-vitro and laboratory research applications only. Research ContextCJC-1295 (No DAC) is studied in in-vitro and animal-model research into the growth hormone-releasing hormone receptor (GHRHR) expressed on somatotroph cells of the anterior pituitary and the associated somatotropic signalling pathway. Its amino acid substitutions at positions 2, 8, 15, and 27 are characterized in the literature for altered stability against dipeptidyl peptidase-IV (DPP-IV) cleavage and plasma proteases relative to native GHRH, while the absence of the Drug Affinity Complex (DAC) is associated with a shorter half-life. These properties make the peptide a subject of interest in growth hormone axis research, metabolic pathway studies, and somatotropic function investigation. Specifications• Sequence: Validated by mass spectrometry (MS/MS)• Purity: ≥ 98% by HPLC• Form: Lyophilized powder• Molecular Weight: 3,367.9 Da• Storage: 2 – 8 °C, keep dry and away from light• Shelf Life: 24 months from manufacture date (sealed) Quality & TestingEvery batch is independently tested by a certified third-party laboratory. A Certificate of Analysis (CoA) confirming purity and identity is available for each batch.
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