Broad-Spectrum Antibiotic Chewable Tablet for Bacterial Infections in Dogs Product Description Clavamox (Amoxicillin Trihydrate/Clavulanate Potassium) Chewable Tablet 375 mg is an FDA-approved prescription antibiotic for dogs only. Each scored brown tablet pairs amoxicillin, a broad-spectrum bactericidal antibiotic, with clavulanate potassium, a beta-lactamase inhibitor, to cover both resistant and non-resistant bacteria. It treats skin, soft tissue, and periodontal infections in dogs caused by susceptible organisms. Please note product may arrive in a HardyPaw Pharmacy vial, manufacturer packaging is shown for reference. Benefits Broad-Spectrum Antibacterial Coverage: Works by combining amoxicillin with clavulanate potassium, giving dogs strong protection against a broad mix of bacteria, including resistant strains. Effective Against Resistant Bacteria: Clavulanate potassium shuts down the enzymes resistant bacteria use to destroy penicillins, keeping amoxicillin active and working as intended. Treats Skin and Soft Tissue Infections: Tackles wounds, abscesses, cellulitis, and pyoderma in dogs linked to Staphylococcus spp., Streptococcus spp., and E. coli. Effective for Periodontal Disease: Shown in clinical settings to clear canine periodontal disease by going after both aerobic and anaerobic bacteria in the gum tissue. Rapid Systemic Absorption: Gets into the bloodstream fast after each dose, building up in the serum, urine, and body tissues where it is needed most. Palatable Chewable Form: In taste trials, more than 83% of dogs ate the tablet within 5 minutes, which takes the hassle out of giving twice-daily doses. Ingredients Active Ingredients Amoxicillin Trihydrate equivalent to 300 mg amoxicillin activity | Clavulanate Potassium equivalent to 75 mg clavulanic acid How to Use Dosage and Administration Instructions Prescription Required: Clavamox Chewable is federally restricted and must only be used under a licensed veterinarian's order with a valid prescription obtained first. For Dogs Only at 375 mg: The 375 mg tablet is for dogs only; never give it to cats. Only the 62.5 mg strength is cleared for both dogs and cats. Recommended Dog Dosage: Give 6.25 mg per lb of body weight twice daily using a combination of whole tablet strengths as prescribed by the veterinarian. Duration for Skin Infections: Treat for 5 to 7 days or 48 hours past symptom resolution; deep pyoderma may need up to 21 days, never beyond 30 days total. Reevaluate if No Response: If the dog shows no improvement after 5 days, stop treatment and contact the vet to reassess the diagnosis and next steps. Administer Full Tablet: Keep the tablet in its foil until just before giving; if the scored tablet breaks, the dog must still eat every piece to get the correct dose. Culture Before Treatment: Run a bacterial culture before starting to confirm susceptibility; treatment can begin right away and be adjusted once results come back. Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet. Additional Information Precautions Penicillin or Cephalosporin Allergy: Never give Clavamox to any dog that has had an allergic reaction to a penicillin or cephalosporin antibiotic in the past. Responsible Antibiotic Use: Giving antibiotics without a confirmed or strongly suspected bacterial infection puts the dog at risk of developing drug-resistant bacteria over time. Not Established in Pregnant Dogs: Safety in pregnant or breeding dogs has not been confirmed; always consult a vet before using Clavamox in these animals. Human Handling Precautions: Avoid touching the tablet with bare skin or mucous membranes; penicillins can trigger allergic reactions in sensitive people, so wash hands thoroughly after each use. Keep Away from All Animals: Store in a locked, secure spot well out of reach of all pets to stop any animal from accidentally getting into the tablets. Possible Side Effects Anorexia and Lethargy: Reduced appetite and low energy are among the most commonly reported reactions in dogs receiving Clavamox based on post-approval reporting data. Vomiting and Diarrhea: Stomach upset, vomiting, and loose stools have been reported after use; contact your vet right away if these symptoms do not clear up. Allergic Reactions: As a semisynthetic penicillin, Clavamox can cause allergic reactions in some dogs; seek veterinary care right away and administer epinephrine or steroids if needed. Storage Information Cool, Dry Storage: Keep Clavamox Chewable Tablets in a cool, dry spot at temperatures no higher than 25°C (77°F) to preserve their full stability and quality. Keep in Foil Until Use: Leave each tablet in its foil strip until just before giving it, as removing it early exposes the tablet to moisture and speeds up breakdown. Keep Out of Reach: Store in a secure location away from children and all animals to stop anyone from accidentally getting into the antibiotic tablets. Shipping & Return We offer ground, express, and priority delivery; see our shipping policy for details. For return instructions or product concerns, please refer to our detailed refund policy. Prescription items are NON-RETURNABLE and NON-REFUNDABLE. Frequently Asked Questions Q1: What infections does Clavamox 375 mg chewable tablet treat in dogs? Ans: Clavamox 375 mg treats skin and soft tissue infections in dogs, including wounds, abscesses, cellulitis, and both superficial and deep pyoderma caused by bacteria like Staphylococcus aureus, Streptococcus spp., and E. coli. It is also used to treat periodontal infections in dogs. Q2: Can Clavamox 375 mg amoxicillin clavulanate chewable tablet be given to cats? Ans: No. The 375 mg Clavamox Chewable Tablet is approved for use in dogs only. The only Clavamox Chewable strength approved for use in both dogs and cats is the 62.5 mg tablet. Always check the label and confirm the correct strength with your veterinarian. Q3: What is the recommended dosage of Clavamox chewable antibiotic for dogs? Ans: Dogs receive 6.25 mg per lb of body weight twice daily. Skin and soft tissue cases usually need 5 to 7 days of treatment, or 48 hours after all signs clear up. Deep pyoderma can take up to 21 days, but treatment should never go past 30 days. Q4: Why does Clavamox combine amoxicillin with clavulanate potassium? Ans: Resistant bacteria produce beta-lactamase enzymes that break down amoxicillin before it can work. Clavulanate potassium shuts down those enzymes, keeping amoxicillin intact and active against both resistant and non-resistant bacterial strains found in dogs. Q5: Is Clavamox penicillin-based antibiotic safe for dogs with a known drug allergy? Ans: No, Clavamox must not be given to any dog with a prior allergic reaction to penicillins or cephalosporins. If a reaction happens during treatment, get veterinary help right away as epinephrine or steroids may be needed. Always tell your vet about known drug allergies upfront. Clinical Research https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=78c3cf22-9151-4f39-a857-d103eca12c93 https://www.mayoclinic.org/drugs-supplements/amoxicillin-and-clavulanate-oral-route/description/drg-20072709 https://www.ncbi.nlm.nih.gov/books/NBK538164/
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