CML-BSA Catalog number: B2017296 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 200 µg Molecular Weight or Concentration: 69.3 kDa Supplied as: Powder Applications: a molecular tool for various biochemical applications Storage: −20°C Keywords: Nε-(1-Carboxymethyl)-L-lysine – Bovine Serum Albumin, Nε-(1-Carboxymethyl)-L-lysine -BSA Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Lee J, Hyon JY, Min JY, Huh YH, Kim HJ, Lee H, Yun SH, Choi CW, Jeong Ha S, Park J, Chung YH, Jeong HG, Ha SK, Jung SK, Kim Y, Han EH. Mitochondrial carnitine palmitoyltransferase 2 is involved in N(ε)-(carboxymethyl)-lysine-mediated diabetic nephropathy Pharmacol Res. 2020 Feb;152:104600. Koito W, Araki T, Horiuchi S, Nagai R. Conventional antibody against Nepsilon-(carboxymethyl)lysine (CML) shows cross-reaction to Nepsilon-(carboxyethyl)lysine (CEL): immunochemical quantification of CML with a specific antibody J Biochem. 2004 Dec;136(6):831-7. Lo MC, Lu CI, Chen MH, Chen CD, Lee HM, Kao SH. Glycoxidative stress-induced mitophagy modulates mitochondrial fates Ann N Y Acad Sci. 2010 Jul;1201:1-7. Lo MC, Chen MH, Lee WS, Lu CI, Chang CR, Kao SH, Lee HM. Nε-(carboxymethyl) lysine-induced mitochondrial fission and mitophagy cause decreased insulin secretion from β-cells Am J Physiol Endocrinol Metab. 2015 Nov 15;309(10):E829-39. Miyahara Y, Ikeda S, Muroya T, Yasuoka C, Urata Y, Horiuchi S, Kohno S, Kondo T. Nepsilon-(Carboxymethyl)lysine induces gamma-glutamylcysteine synthetase in RAW264.7 cells Biochem Biophys Res Commun. 2002 Aug 9;296(1):32-40. Lo MC, Chen MH, Hsueh YT, Kuo YT, Lee HM. Alpha-lipoic acid suppresses N(ε)-(carboxymethyl) lysine-induced epithelial mesenchymal transition in HK-2 human renal proximal tubule cells Free Radic Res. 2018 Dec;52(11-12):1387-1397. Svistounov DN, Berg TJ, McCourt PA, Zykova SN, Elvevold KH, Nagai R, Horiuchi S, Smedsrod BH. Lack of recognition of Nepsilon-(carboxymethyl)lysine by the mouse liver reticulo-endothelial system: implications for pathophysiology Biochem Biophys Res Commun. 2003 Oct 3;309(4):786-91. Chen Y, Niu W, Chao YC, He Z, Ding R, Wu F, Liang C. Alagebrium targets the miR-27b/TSP-1 signaling pathway to rescue N(ε)-carboxymethyl-lysine-induced endothelial dysfunction Am J Transl Res. 2019 Mar 15;11(3):1569-1580. eCollection 2019. Tang SC, Chan LY, Leung JC, Cheng AS, Lin M, Lan HY, Lai KN. Differential effects of advanced glycation end-products on renal tubular cell inflammation Nephrology (Carlton). 2011 May;16(4):417-25.
