Description:Better suited for cooler, drier climates and sensitive skin. Enzyme-Activated Arbutin cream to brighten skin. Directions:Use nightly before tretinoin for best results. This cream is made to order so there are no returns. Key Ingredients: High Potency, Enzyme-Activated Arbutin Glycolic acid Vitamin C ester Vitamin E Green Tea If the user does not currently have a retinoid routine, we recommend not starting one at the same time as the Coleman Compound. Instead, establish a routine with one first, allow approximately 30 days to adjust, and then introduce the other. Starting the Coleman Compound first is fine. *****This Product has active Ingredients that may cause skin irritation. Compounded to order, use within 4 months for optimal quality. Not recommended for use during pregnancy or while breastfeeding. There are no refunds or returns. All sales final*****