💊 Colistin 5% Powder – General Description Generic name: Colistin (also known as Polymyxin E)Pharmaceutical form: Powder (for oral use in animals or for reconstitution, depending on formulation)Concentration: 5% (i.e., 50 mg of colistin per gram of product, depending on manufacturer) ⚙️ Composition Active ingredient: Colistin (as colistin sulfate or colistimethate sodium) – 5% Excipients: Inert carrier (such as lactose or dextrose) up to 100% 🧫 Mechanism of Action Colistin is a polypeptide antibiotic that acts by disrupting the bacterial cell membrane, causing leakage of cellular contents and bacterial death.It is mainly effective against Gram-negative bacteria, including: Escherichia coli Salmonella spp. Klebsiella spp. Pseudomonas aeruginosa 🐄 Common Uses (Veterinary) Colistin 5% powder is widely used in veterinary medicine (poultry, swine, calves) for the treatment and prevention of gastrointestinal infections caused by susceptible Gram-negative bacteria, such as: Bacterial enteritis Colibacillosis Salmonellosis 💧 Route of Administration Oral use, usually administered through drinking water or feed(Dosage depends on animal species, weight, and severity of infection) ⚠️ Precautions Do not use in animals with hypersensitivity to colistin. Observe withdrawal periods before slaughter or milk/egg collection. Overuse can lead to antimicrobial resistance, so use under veterinary supervision.
