Compeed Callus Patches work like a second skin for instant pain relief and fast natural healing. When the skin is subjected to continuous pressure it responds by creating a thick layer of dead skin known as a callus. These medium sized plasters are ideal for soothing pain and cushioning the area from further pressure. Pack Size: 6 Plasters (Medium Size) How to Use: Clean and dry skin before use. Do not touch adhesive side of plaster. Leave in place until it starts to detach. May be up to several days.Diabetics: consult doctor before use.See full instructions & warnings inside. Warnings Diabetics: Consult a doctor before use. Contains: Artificial Elastomer, Tackifier Rasins, Hydrocolloid Particles (Sodium Carboxymethyl Celluose) Plasticiser, Polyurethane Film.