Integrative Therapeutics Cortisol Manager Cortisol follows a natural daily rhythm — highest in the early morning to support alertness and energy, gradually declining through the day into evening. Chronic stress, poor sleep, and HPA axis dysregulation can disrupt that pattern, leaving cortisol elevated at night when it should be low. The result is that familiar combination of wired-but-tired: difficulty winding down, poor sleep quality, and a stress response that never quite switches off. Cortisol Manager addresses this with two targeted blends. The stress-reducing blend combines Sensoril ashwagandha — a clinically studied form shown to significantly reduce serum cortisol in placebo-controlled trials — with L-theanine, which promotes calm without sedation. The cortisol-reducing blend adds magnolia bark extract, epimedium, and phosphatidylserine, which has well-documented research behind its role in blunting the cortisol response to physiological stress. The formula contains no melatonin and is non-habit forming, making it appropriate for nightly use. One tablet before bed, with the option to increase to two during periods of higher stress. Not for use during pregnancy or nursing. May cause drowsiness — avoid driving after use. Contains soy. Gluten-free | Dairy-free | Vegan These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.