Remodeling next-generation Crème M.E.C. is Biologique Recherche’s next-generation answer to skin aging—designed not to simply target wrinkles, but to remodel the skin’s foundational structure. This advanced bi-gel cream works at the level of the extracellular matrix (ECM), the architectural system responsible for skin strength, density, elasticity, and resilience. By reinforcing the four essential pillars of the ECM—collagen, elastin, glycosaminoglycans (GAGs), and glycoproteins—Crème M.E.C. helps restore structural cohesion, improve firmness, and visibly smooth fine lines across the face, neck, and décolleté. Recommended for: Skin showing loss of firmness, density, and structural support Fine lines and early to advanced signs of aging Skin lacking resilience, elasticity, or “bounce” All skin types, including sensitive or compromised skin Clients seeking long-term skin remodeling rather than short-term correction Benefits: Helps remodel and strengthen the skin’s extracellular matrix Improves firmness, elasticity, and overall skin density Visibly smooths fine lines on face, neck, and décolleté Enhances skin integrity and dermal-epidermal cohesion Leaves skin with a refined, smooth, “porcelain-like” finish How to use: Apply morning and/or evening to clean skin after your recommended Biologique Recherche serums Gently massage over face, neck, and décolleté until fully absorbed Loshen & Crem’s recommendation: Crème M.E.C. is ideal for clients who understand that aging is structural, not superficial. We love this cream for skin that needs global support rather than targeted line correction. Pair it with serums focused on hydration, cellular regeneration, or barrier support to amplify long-term results. This is a sophisticated daily cream for those investing in the future of their skin. Ingredients: Collagen complex – Supports synthesis and organization of multiple collagen types to reinforce skin structure and density Elastin-supporting actives – Help inhibit elastin degradation while improving firmness and elasticity Glycosaminoglycans (including hyaluronic-acid-linked structures) – Enhance hydration reservoirs and plumping within the ECM Glycoprotein-supporting actives – Strengthen the dermal-epidermal junction and improve overall skin integrity Full INCI list WATER (AQUA), GLYCERIN, COCO-CAPRYLATE/CAPRATE, CAPRYLIC/CAPRIC TRIGLYCERIDE, ISOSTEARYL ALCOHOL, MALTODEXTRIN, METHYLPROPANEDIOL, BUTYLENE GLYCOL COCOATE, LAUROYL LYSINE, UNDECANE, MEDICAGO SATIVA (ALFALFA) EXTRACT, SACCHARIDE HYDROLYSATE, POLYGLUTAMIC ACID, HAEMATOCOCCUS PLUVIALIS EXTRACT, SODIUM HYALURONATE, HYDROLYZED COLLAGEN, ETHYLCELLULOSE, LECITHIN, TOCOPHEROL, PENTYLENE GLYCOL, SORBITAN ISOSTEARATE, 1,2-HEXANEDIOL, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, TRIDECANE, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, POLYSORBATE 60, CAPRYLYL GLYCOL, PHENYLPROPANOL, SODIUM HYDROXIDE, SODIUM BENZOATE, POTASSIUM SORBATE. Warning: the lists of ingredients used in Biologique Recherche products are updated regularly. Before using a Biologique Recherche product, please read the list of ingredients on its packaging to ensure that the ingredients are suitable for your personal use. In case of an allergy, please consult. BR Skin Reaction Policy 📄 At Loshen & Crem, we want to ensure you have the best possible experience with Biologique Recherche. Before purchasing any Biologique Recherche product, we highly recommend booking a consultation with one of our estheticians. Consultations are available virtually through Google Meet or in person at our Edmonton boutique. An appointment is required. In the event of a reaction, Biologique Recherche requires photos of the reaction and the product, the lot number found on the product or the bottom of the box, and proof of a consultation with one of our estheticians before they can review the concern. If you choose to purchase without a consultation and experience a reaction, we will be unable to provide a refund. Our team is always happy to answer your questions and help you select the products best suited to your skin.
